In 2018, Transcranial Pulse Stimulation (TPS^®) with the NEUROLITH^® system was the first, and hitherto only, procedure of its kind to obtain market authorization for the »treatment of the central nervous system of patients with Alzheimer’s disease«. TPS_^® was developed by STORZ MEDICAL in collaboration with a team of researchers from the Medical University of Vienna (Department of Neurology), led by Professor Roland Beisteiner, and Dr. Henning Lohse-Busch, Rheintalklinik, Bad Krozingen. In December 2019, the prestigious journal »Advanced Science« published a study, in which Beisteiner et al. evaluate the method and present first treatment results. The presented data shows that it is possible to improve brain performance with TPS^® and that there is a long-term effect.